Premna serratifolia

Trees, to 7 m high. Leaves simple, opposite, estipulate; petiole 4–14 mm, slender, pubescent, grooved above; lamina 2.5-8.5 x 2–7.2 cm, elliptic, elliptic-oblong, base acute, obtuse, subcordate or rounded, apex acuminate, mucronate, obtuse, margin entire or subserrate, glabrous above except along the appressed midrib, chartaceous; lateral nerves 3-5 pair, pinnate, prominent, puberulous beneath; intercostae reticulate, obscure. Flowers bisexual, greenish-white, in terminal corymbose panicled cymes; bracts small; calyx small campanulate, 2 lipped, 5 lobed; corolla tube short, villous inside, lobes 5; stamens 4, didynamous, inserted below the throat of the corolla tube; anther ovate; ovary superior, 2-4-celled, ovules 4; style linear; stigma shortly bifid. Fruit a drupe, seated on the calyx, globose, purple; seeds oblong.

It mostly grows in moist sandy soil and scrub jungles along seacoasts and mangrove forests. In the Philippines, particularly in Cebu Island, it is usually found in the interior, watery forests of Southern Cebu.

The plant is extensively used in Indian traditional medicine. Studies on the root wood of P. serratifolia led to the isolation of acteoside, a glucoside derivative. The root bark of the plant which showed biological activities have also shown to contain a potent cytotoxic and antioxidant diterpene, 11,12,16-trihydroxy-2-oxo-5-methyl-10-demethyl-abieta-1[10],6, 8,11,13-pentene.